Adjunct hormones like melatonin and DHEA can play powerful roles in breast cancer care—even alongside conventional treatments. In this lesson, you’ll explore how melatonin acts as a natural SERM and aromatase inhibitor, and why DHEA may actually offer anti-cancer benefits through its action on estrogen receptor beta. Nico also unpacks how high-dose estradiol paradoxically triggers cell death in certain cases, and challenges assumptions about estrogen receptor blockers like tamoxifen.